Role frozen section breast tumor

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Frozen section analysis for breast cancer could save time, anxiety

Frozen section analysis for breast cancer could save time, anxiety -- ScienceDaily

Intraoperative frozen section examination IFSE during breast cancer surgery can partly reflect the status of surgical treatment since the surgical method used directly determines the purpose of IFSE use in disease management. This study aims to investigate the application of, changing trends in, and factors influencing IFSE in the management of female breast cancer in China. A total of 2, Our results show that the purpose of IFSE in the surgical treatment of breast cancer in China is gradually approaching that in developed countries. We believe that policymakers must address the differences in breast cancer treatment based on the socioeconomic status of patients.

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The accuracy of frozen section analysis in ultrasound- guided core needle biopsy of breast lesions

Pathologists have an important role in medicine, and nowhere is this more evident than in the care of breast cancer patients. In clinical care, only pathologists make the diagnosis of breast cancer. We determine whether a tumor is benign or malignant, as well as how far the tumor has grown within the breast and whether it has spread to lymph nodes or other organs. We also determine kinds of proteins the tumor expresses, such as ER and HER-2, and our analysis determines whether or not the tumor should be treated with endocrine therapy like tamoxifen, among others or anti-HER-2 therapy like trastuzumab, among others.

Margin status is a robust predictor of local recurrence in women undergoing breast-conserving surgery for early-stage breast cancer. The goal of surgical resection with lumpectomy is to achieve negative margin status. A positive margin significantly increases the risk for local recurrence. Unfortunately, margin status is usually not known until pathologic analysis days or weeks following surgery.

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